Protective effect of ethanolic extract and raw juice of Solanum betaceum on aluminum induced oxidative stress and associated memory deficits in rats

-Anne P.N. Kengne; Rodrigue Tidjong; Dieudonné Kuate; Hermine T. Doungue; Prosper N.Takam; Inelle Makamwé

Abstract Background: Oxidative stress is known to contribute to the mechanisms underpinning the pathogenesis of neurodegenerative diseases. Previous studies have identified the presence of flavonoids as the major constituents of Solanum betaceum (SB) with antioxidant activity. This work aims at investigating the protective effect of ethanolic extract and raw juice of Solanum betaceum (SB) on aluminum induced oxidative stress and associated memory deficits in Wistar rats. Methods: Memor...

Therapeutic Impacts of Garlic Varieties on Hyperlipidemia Induced In Male Wistar Rats

-René Nia; Abia S. Njang; Ufuan A. Achidi; Bernard Tiencheu; Germain S. Taiwe

Abstract Background: Every year, cardiovascular diseases take the lives of 17.7 million people accounting for 31% of all global deaths with atherosclerotic cardiovascular disease being the leading cause of mortality. Interestingly, hyperlipidemia is an important modifiable risk factor contributing to atherosclerosis. Methods: Qualitative phytochemical screenings was done according to standard protocols. For hyperlipidemia protocol, animals were divided randomly into 4 groups of 6 rats eac...