Abstract
Background: Male infertility and erectile dysfunction are the main conditions associated with male reproductive function disorders. Testosterone is the main hormone that regulates male reproductive function, while nitric oxide is a potent vasodilator involved in the erectile process.
Methods: This study was conducted to evaluate in vitro the potential of the aqueous extract of six Cameroonian medicinal plants traditionally used for male reproductive function: Palisota ambigua, Te...
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In-vitro anti-salmonella activity of methanol and aqueous extracts and their associations of Psidium guajava and Carica papaya leaves
Background: Typhoid fever is a major public health problem and endemic especially in some developing countries. The present study was aimed at determining the anti-salmonella potentials of Psidium guajava (PG) and Carica papaya (CP) leaves extract association in-vitro.
Methods: The plant materials were extracted both in methanol and water separately. The methanol extract was concentrated using a rota-evaporator while the aqueous was dried in an oven. Phytochemical screening was done for the p...
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Comparative study of potent anti-amoebic and anti-inflammatory activities of different extracts from Sida rhombifolia (L)
Background: Sida rhombifolia (L) is a medicinal plant from tropical regions belonging to the Malvaceae family and the plantea kingdom. It is known for its multiple pharmacological properties. The aim of this work was to evaluate the anti-amoebic, and anti-inflammatory potential of Sida rhombifolia aqueous and ethanolic leaf and stem extracts harvested in two localities of Cameroon (Yaoundé and Massangam in the Centre and West regions, respectively). Methods: The anti-amoebic activity was evaluat...
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Chemical constituents and antibacterial activity of Annickia chlorantha (Oliv.) Setten & Maas (Annonaceae) and their chemophenetic significance
Abstract
Background: Annickia chlorantha (Annonaceae) is an ornamental tree, which may grow up to 30 m high with dense foliage and spreading crown. It is used in traditional medicine for its anti-infective properties particularly in the treatment of fungal infections, malaria, hepatitis, jaundice and other bacterial infections. This study describes the chemical and antibacterial investigation of ethanol extract of the stem bark of A. chlorantha.
Methods: The compounds were obtained by sep...
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Antibacterial and antibiotic-potentiation activity of Coffea arabica and six other Cameroonian edible plants against multidrug-resistant phenotypes
Abstract
Background: Medicinal plants have always played an important role in human health. Many plants are traditionally used as drugs against microbial infections. In this study, a panel of seven methanol extracts from Cameroonian edible was assessed for their antibacterial potentiality against multidrug-resistant Gram-positive and Gram-negative bacteria.
Methods: The microdilution technique using a 96-well plate was used to assess the minimal inhibitory concentration (MIC) and minimal ...
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Comparative study of polyphenols quantification, total phenolic content, and antioxidant activities of the fruits of three plants of the family of Solanaceae: Lycium ruthenicum, Lycium barbarum, and Lycium Chinense
Abstract
Background: Fruits from L. ruthenium, L. barbarum, and L. Chinense, of the family Solanaceae are well-known in traditional Chinese medicine and have been used as popular functional foods, with a large variety of beneficial health effects.
Methods: In The present study, ethanolic extracts (30%) of lycium fruits were analyzed by high-performance liquid chromatography (HPLC). Total phenolic content was determined together with the quantification of seventeen (17) phenolic compounds....
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Cellular modes of action of the methanol extract from the aerial parts of Psychotria sycophylla (K.Schum.) Petit (Rubiaceae) against multidrug-resistant bacteria
Abstract
Background: Infectious diseases caused by multidrug-resistant bacteria (MDR) remain a global health issue. The population uses several plants from the Cameroonian pharmacopeia to treat bacterial infections. The methanol extract from the aerial parts of Psychotria sycophylla (K.Schum.) Petit (Rubiaceae) (PSA) previously showed antibacterial activities against MDR bacteria. In the present study, the antibacterial activities of PSA were determined in the presence of an efflux pump inhi...
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Diversity of aggressive Aedinian fauna and susceptibility of Aedes albopictus (Skuse, 1894) to Ageratum conyzoides L., 1753 and Chromolaena odorata L. Robinson, 1970 (Asteraceae) essential oils in some towns from southern Cameroon
Abstract
Background: A good knowledge of Aedes diversity and their biting cycle is necessary for better planning of vector control interventions against arboviruses diseases. This study aims to determine the diversity of Aedes and the biting cycle of Aedes albopictus in suburban as well as urban areas of Douala, Kribi, and Ayos to propose a method for vector control based on Ageratum conyzoides L., 1753 and Chromolaena odorata L., 1970 (Asteraceae) essential oil.
Methods: Larvae were sam...
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Chemical constituents and antibacterial activity from the fruits of Ficus sur Forssk
Abstract
Background: Ficus sur Forssk is used in traditional African medicine in the treatment of skin diseases, epilepsy, jaundice, pain, inflammation, anemia, sexually transmitted diseases, and diarrhea. We described here the chemical study and antibacterial properties of F. sur ethanol extract.
Methods: Separation and isolation of compounds were performed using common chromatographic methods. The structures of compounds were determined by spectrometric and spectroscopic analyses includ...
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Antifungal activity of endophytic Fusarium oxysporum from Cola acuminata against Candida albicans isolates from HIV-infected patients
Abstract
Background: The Human Immunodeficiency Virus (HIV) infection has exacerbated the occurrence of opportunistic diseases with Candida infection being the most prominent. Unfortunately, the growing ineffectiveness of the available antifungal drugs along with the emergence of new multi-resistant strains further worsen the matter. In the search for new active molecules, the present study aims at investigating the optimal growth conditions for the production of antifungal metabolites from ...
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