Table of Contents Volume4, issue 1; July 31, 2021

Table of Contents Volume4, issue 1; July 31, 2021 (Available at: https://www.investchempharma.com/wp-admin/term.php?taxonomy=volume&tag_ID=54&post_type=post&wp_http_referer=%2Fwp-admin%2Fedit-tags.php%3Ftaxonomy%3Dvolume) https://dx.doi.org/10.31183/imcp.2021.v4i1   Research Article   1- Effects of stifled cooking on the quality and lipid-lowering potential of oils extracted from two species of pumpkin seeds (Citrullus lanatus and Cucumeropsis mannii)   ...
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Antioxidant and antifungal activities of Myrianthus arboreus P. Beauv. (Moraceae), Allanblackia gabonensis Pellegr. (Clusiaceae) and three other Cameroonian medicinal plants

Abstract Background: Biological activities of medicinal plants make them attractive alternative complementary medicines. Therefore, this study aimed to assess the antioxidant and antifungal activities of the methanol extract of Myrianthus arboreus, Allanblackia gabonensis, Gladiolus quartinianus, Peperomia fernandopoiana and Vepris soyauxii. Methods: Total phenolic contents (TPC) and flavonoid contents (FC) were evaluated using standard methods. The antioxidant activity of the extracts wa...
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Antidiabetic activity of aqueous extract of leaves of Cnestis ferruginea vahl ex DC. (Connaraceae) on alloxan-induced diabetic mice

Abstract Background: Cnestis ferruginea is a plant species widely used in the traditional african medicine to treat diabetes mellitus. The present study aimed to evaluate the antidiabetic activities of the aqueous extract of the leaves of Cnestis ferruginea (AECF) in diabetic mice. Methods: The mice were grouped into five groups of five animals per group: Group A was not induced with alloxan, Group B animals were induced but not treated, Group C animals were treated with 500 mg / kg of BW...
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Anti-oedematous and antinociceptive activities assessment of stem bark aqueous extract of Ficus exasperata Vahl. (Moraceae) in rat and mice.

Abstract Background: Ficus exasperata Vahl. (Moraceae) is widely used in African traditional medicine for the treatment of various diseases. The present study is undertaken to assess the anti-oedematous and antinociceptive activities of the stem bark aqueous extract of Ficus exasperata in mice and rats. Methods: The anti-oedematous activity was investigated following carrageenan or histamine-induced rat paw oedema models.  Antinociceptive activity was evaluated using acetic acid induced w...
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In vitro antibacterial and antibiotic-potentiation activities of five edible plant extracts and mode of action against several MDR Gram-negative phenotypes

Abstract Background: Bacterial infections involving the multidrug resistant (MDR) strains are among the top leading causes of death throughout the world. Healthcare system across the globe has been suffering from an extra-ordinary burden in terms of looking for the new and more potent antimicrobial compounds. The aim of the present study was to determine the antibacterial activity of some Cameroonian edible plants (Garcinia lucida bark, Phoenix dactylifera pericarps, Theobroma cacao pod, Sol...
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Antibiotic-potentiation activities of three animal species extracts, Bitis arietans, Helix aspersa, and Aristaeomorpha foliacea and mode of action against MDR Gram-negative bacteria phenotypes

Abstract Background: In recent years, drug resistance to human pathogenic bacteria has been commonly reported from all over the world. As antimicrobial activities of most medicinal plants and antibiotics have been already explored, it is more important to make investigations on animal species mainly invertebrates which could constitute an efficient source of antimicrobial molecules. This work was aimed at contributing to the fight against microbial resistance through the study of antibacteri...
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Effects of stifled cooking on the quality and lipid-lowering potential of oils extracted from two species of pumpkin seeds (Citrullus lanatus and Cucumeropsis mannii)

Abstract Background: Hyperlipidemia is a major risk factor for cardiovascular diseases. Cucumeropsis mannii and Citrullus lanatus commonly called pumpkin seeds or egussi, the oil-rich seeds, have already demonstrated hypolipidemic activity. In Africa, these seeds are popularly used in the preparation of local foods. During that thermal process, the fatty acid content of pumpkin seeds’ oils may be altered in their functionality. Thus, this work aims at studying the effect of stifled cooking o...
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Table of Contents Volume3, issue 2; December 31, 2020

Table of Contents Volume3, issue 2; December 31, 2020 (Available at: https://www.investchempharm.com/volume/volume3/issue-2/) https://dx.doi.org/10.31183/imcp.2020.v3i2   Research Article   1- Antidepressant potential of butanol fraction of Milicia excelsa (Moraceae) leaf in mice.   Authors: Lateef A. Akinpelu; Julius K. Olaonipekun; Samuel S. Agboola; Theophilus. A. Adegbuyi; Idowu J. Olawuni; Idris A. Oyemitan; Gbola Olayiwola. Investigational Medicinal Chemistr...
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Mechanisms of action of roots crude extract and adianthifolioside GS1 from Albizia adianthifolia (Fabaceae) against MDR Gram-negative enteric bacteria

Abstract   Background: The Cameroonian pharmacopoeia is full of many plants used amongst population to treat various infections. Albizia adianthifolia (Schum.) is one of these plants and therefore several previous studies have reported the antibacterial activities of the crude methanol extract of the roots of this plant as well as those of some of its isolated compounds. In this study, the methanol root extract, and its isolated compound "adianthifolioside GS1" were evaluated on bact...
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Antiamnesic effect of aqueous lyophilisate of Drymaria cordata on scopolamine-induced amnesia and oxidative stress in mice

Abstract Background: Learning and memorization are the so-called higher functions of the brain whose alteration is at the origin of neurodegenerative diseases. Drymaria cordata (D. cordata) is a plant used in Cameroon to treat disorders such as convulsions and ulcers. The aim of this study was to evaluate the anti-amnestic effects of D. cordata on scopolamine-induced amnesia in mice and its potential antioxidant properties. Methods: The Morris water maze was used to evaluate the spatial m...
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