Abstract
Background: The inappropriate use of antibiotics against bacterial infections leads to increased bacterial drug resistance. In the present study, the effectiveness of methanol extracts from the leaves and flowers of Ocimum basilicum and the roots of Sarcocephalus latifolius against multidrug-resistant (MDR) Gram-negative bacteria overexpressing efflux pumps was assessed.
Methods: The antibacterial properties of crude extracts (botanical, with and without phenylalanine arginine β-...
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Table of Contents
Volume7, issue 2; August 30; 2024
https-dx-doi-org-10-31183-imcp-2024-v7i2
Review Article
1- The best African plant-derived antibacterial products for clinical perspectives: The state-of-the-art
Authors: Victor Kuete. Investigational Medicinal Chemistry and Pharmacology 2024 7(2):94. doi: https://dx.doi.org/10.31183/imcp.2024.00094
Research Article
1- Ethnopharmacology and anthelmintic screening of some plants used in traditional medicine in the Far-North of Cameroon
Authors: Issiyakou Haman; Ngwafu Nancy Ngwasiri; Ahmadou Adamou; Elias Darahalaye Abladam; Nicolas Yanou Njintang; Dieudonné Ndjonka. Investigational Medicinal Chemistry and Pharmacology 2024 7(2):95. doi: https://dx.doi.org/10.31183/imcp.2024.00095
2- Antibacterial activity of Sarcocephalus latifolius and Acacia sieberiana and the effect of their association with antibiotics against multidrug-resistant Staphylococcus aureus
Authors: Larissa Mpude; Ancela W. B. Yendze; Derick J. Assonfack; Eric Cadet; Valaire Y. Matieta; Junior F. Megaptche; Armelle T. Mbaveng; and Victor Kuete. Investigational Medicinal Chemistry and Pharmacology 2024 7(2):96. doi: https://dx.doi.org/10.31183/imcp.2024.00096
3- Antibacterial activity and antibiotic-potentiating effects of methanol extracts from Ocimum basilicum and Sarcocephalus latifolius against multidrug-resistant Gram-negative bacteria overexpressing efflux pumps
Authors: Eric Cadet; Derick J. Assonfack; Ancela W. B. Yendze; Larissa Mpude; Valaire Y. Matieta; Jenifer R. N. Kuete; Junior F. Megaptche; Idrios N. Bonsou; Victor Kuete; and Armelle T. Mbaveng. Investigational Medicinal Chemistry and Pharmacology 2024 7(2):97. doi: https://dx.doi.org/10.31183/imcp.2024.00097
Antibacterial activity of Sarcocephalus latifolius and Acacia sieberiana, and the effect of their association with antibiotics against multidrug-resistant Staphylococcus aureus
Abstract
Background: Infectious diseases continue to wreak havoc around the world causing directly or indirectly 17 million deaths per year. The present study was carried out to evaluate the in vitro antibacterial activity of the methanol extracts from the root of Sarcocephalus latifolius and from the leaves of Acacia siberiana, and their ability to potentiate the action of antibiotics against multidrug-resistant (MDR) Staphylococcus aureus.
Methods: The antibacterial assays were performe...
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Ethnopharmacology and anthelmintic screening of some plants used in traditional medicine in the Far-North of Cameroon
Background: The use of traditional medicinal plants in Cameroon for the treatment of intestinal helminthiasis is a common practice among traditional healers and livestock breeders. However, the use of ethnopharmaceutical products for their anthelmintic activities against Haemonchus contortus has been poorly addressed in the Far-North region of Cameroon, therefore justifying the need to bridge this gap.
Methods: An ethno-pharmacological survey was conducted among livestock breeders and traditi...
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The best African plant-derived antibacterial products for clinical perspectives: The state-of-the-art
Abstract
Background: The global burden of bacterial infections remains a serious health concern. In the present review, we have summarized the best botanicals and phytochemicals from the flora of Africa that deserve clinical studies to develop novel antibacterial drugs to combat enterobacteria, Pseudomonas aeruginosa, Gram-positive bacteria, and mycobacteria.
Methods: Data were retrieved from scientific databases such as PubMed, Scopus, ScienceDirect, Google Scholar, and Web of Science us...
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