Abstract
Background: The resistance of gastrointestinal worms to synthetic anthelmintics (Levamisole) leads us to highlight the Cameroonian pharmacopoeia. The main objective of the present work is to look for an alternative treatment for haemonchosis, based on active secondary metabolites, from Portulaca oleracea, with less or no side effects and accessible to all.
Methods: The Haemonchus contortus cycle test was performed at varying concentrations. Levamisole and PBS were the positive an...
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Volume4, issue 1; July 31, 2021
https://dx.doi.org/10.31183/imcp.2021.v4i1
Volume4, issue 2; December 31, 2021
https://dx.doi.org/10.31183/imcp.2021.v4i2
GC-MS analysis and physiochemical properties of Enterolobium cyclocarpum (elephant ear) seed oil
Abstract
Background: The present study aimed to extract, evaluate the physicochemical properties, and chemical characterization of the seed Enterolobium cyclocarpum. E. cyclocarpum is a legume of the Leguminosae family. It is used as foliage, for animal feeding and oil is extracted for several application in folk medicine for the treatment of sore throat, colds, diarrhea, headache, intestinal ailments, and stomachache. The leaf infusion is used as a laxative In the West Indies; seeds are che...
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Testicular antioxidants and testosterone enhancing effects of the hydro-ethanolic extract of Rauvolfia vomitoria (Apocynacaea) in male Wistar rats
Abstract
Background: Natural products such as extracts of plants have been seen as a possible alternative to conventional therapies in the treatment and management of male infertility. This study aimed at investigating the testicular antioxidant and testosterone enhancing ability of the hydro-alcoholic extract of Rauvolfia vomitoria in male rats.
Methods: Twenty-four male rats were divided into four groups of 6 rats each, treated daily with either vehicle (distilled water; 5 mL/kg) or hyd...
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Phytochemical analysis and antibiotic-modulating activity of Cocos nucifera, Glycine max and Musa sapientum methanol extracts against multidrug resistant Gram-negative bacteria
Abstract
Background: The rapid emergence of multidrug resistant (MDR) bacteria is occurring worldwide, endangering the efficacy of antibiotics, which have transformed medicine and saved millions of lives. Antibiotic-resistant infections are already widespread in the Sub-Saharan Africa and across the globe. To extend the search for new and more efficient antimicrobial drugs from natural sources, this work has been carried out to study the phytochemical composition and the antibacterial activi...
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Table of Contents Volume4, issue 1; July 31, 2021
Table of Contents
Volume4, issue 1; July 31, 2021
(Available at: https://www.investchempharma.com/wp-admin/term.php?taxonomy=volume&tag_ID=54&post_type=post&wp_http_referer=%2Fwp-admin%2Fedit-tags.php%3Ftaxonomy%3Dvolume)
https://dx.doi.org/10.31183/imcp.2021.v4i1
Research Article
1- Effects of stifled cooking on the quality and lipid-lowering potential of oils extracted from two species of pumpkin seeds (Citrullus lanatus and Cucumeropsis mannii)
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Antioxidant and antifungal activities of Myrianthus arboreus P. Beauv. (Moraceae), Allanblackia gabonensis Pellegr. (Clusiaceae) and three other Cameroonian medicinal plants
Abstract
Background: Biological activities of medicinal plants make them attractive alternative complementary medicines. Therefore, this study aimed to assess the antioxidant and antifungal activities of the methanol extract of Myrianthus arboreus, Allanblackia gabonensis, Gladiolus quartinianus, Peperomia fernandopoiana and Vepris soyauxii.
Methods: Total phenolic contents (TPC) and flavonoid contents (FC) were evaluated using standard methods. The antioxidant activity of the extracts wa...
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Antidiabetic activity of aqueous extract of leaves of Cnestis ferruginea vahl ex DC. (Connaraceae) on alloxan-induced diabetic mice
Abstract
Background: Cnestis ferruginea is a plant species widely used in the traditional african medicine to treat diabetes mellitus. The present study aimed to evaluate the antidiabetic activities of the aqueous extract of the leaves of Cnestis ferruginea (AECF) in diabetic mice.
Methods: The mice were grouped into five groups of five animals per group: Group A was not induced with alloxan, Group B animals were induced but not treated, Group C animals were treated with 500 mg / kg of BW...
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Anti-oedematous and antinociceptive activities assessment of stem bark aqueous extract of Ficus exasperata Vahl. (Moraceae) in rat and mice.
Abstract
Background: Ficus exasperata Vahl. (Moraceae) is widely used in African traditional medicine for the treatment of various diseases. The present study is undertaken to assess the anti-oedematous and antinociceptive activities of the stem bark aqueous extract of Ficus exasperata in mice and rats.
Methods: The anti-oedematous activity was investigated following carrageenan or histamine-induced rat paw oedema models. Antinociceptive activity was evaluated using acetic acid induced w...
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In vitro antibacterial and antibiotic-potentiation activities of five edible plant extracts and mode of action against several MDR Gram-negative phenotypes
Abstract
Background: Bacterial infections involving the multidrug resistant (MDR) strains are among the top leading causes of death throughout the world. Healthcare system across the globe has been suffering from an extra-ordinary burden in terms of looking for the new and more potent antimicrobial compounds. The aim of the present study was to determine the antibacterial activity of some Cameroonian edible plants (Garcinia lucida bark, Phoenix dactylifera pericarps, Theobroma cacao pod, Sol...
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Antibiotic-potentiation activities of three animal species extracts, Bitis arietans, Helix aspersa, and Aristaeomorpha foliacea and mode of action against MDR Gram-negative bacteria phenotypes
Abstract
Background: In recent years, drug resistance to human pathogenic bacteria has been commonly reported from all over the world. As antimicrobial activities of most medicinal plants and antibiotics have been already explored, it is more important to make investigations on animal species mainly invertebrates which could constitute an efficient source of antimicrobial molecules. This work was aimed at contributing to the fight against microbial resistance through the study of antibacteri...
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